Sarafotoxins S6: Several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart

Chikahisa Takasaki*, Nobuo Tamiya, Avner Bdolah, Zvi Wollberg, Elazar Kochva

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

175 Scopus citations

Abstract

Sarafotoxins S6: several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart. Toxicon 26, 543 - 548, 1988. - Three isotoxins, named sarafotoxins S6a1, S6b and S6c, with strong cardiotoxic activity were isolated from the venom of a snake, Atractaspis engaddensis. All three sarafotoxins are homologous peptides (four or less than four residue replacements) consisting of 21 amino acid residues. Their structure and activity are novel among snake venom components.

Original languageEnglish
Pages (from-to)543-548
Number of pages6
JournalToxicon
Volume26
Issue number6
DOIs
StatePublished - 1988

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