Saldedines A and B, dibromo proaporphine alkaloids from a Madagascan tunicate

Hagit Sorek; Amira Rudi; Israel Goldberg; Maurice Aknin; Yoel Kashman

doi:10.1021/np800714k

Saldedines A and B, dibromo proaporphine alkaloids from a Madagascan tunicate

Hagit Sorek, Amira Rudi, Israel Goldberg, Maurice Aknin, Yoel Kashman^*

^*Corresponding author for this work

School of Chemistry

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Two new dibromo proaporphine alkaloids, designated saldedines A (1) and B (2), were isolated from an unidentified tunicate collected at Salary Bay, Madagascar. Saldedines A and B are the first marine proaporphine alkaloids. Their structures were elucidated by extensive spectroscopic means, and the structure of 1 was confirmed by single-crystal X-ray diffraction analysis. Both saldedines A and B were tested for toxicity to brine shrimp and showed moderate activity.

Original language	English
Pages (from-to)	784-786
Number of pages	3
Journal	Journal of Natural Products
Volume	72
Issue number	4
DOIs	https://doi.org/10.1021/np800714k
State	Published - 24 Apr 2009

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abstract = "Two new dibromo proaporphine alkaloids, designated saldedines A (1) and B (2), were isolated from an unidentified tunicate collected at Salary Bay, Madagascar. Saldedines A and B are the first marine proaporphine alkaloids. Their structures were elucidated by extensive spectroscopic means, and the structure of 1 was confirmed by single-crystal X-ray diffraction analysis. Both saldedines A and B were tested for toxicity to brine shrimp and showed moderate activity.",

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Saldedines A and B, dibromo proaporphine alkaloids from a Madagascan tunicate

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