Routine inclusion of level IV in neck dissection for squamous cell carcinoma of the larynx: Is it justified?

Avi Khafif*, Dan M. Fliss, Ziv Gil, Jesus E. Medina

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Background. Dissection of levels II-IV as part of an elective or therapeutic neck dissection is common practice during laryngectomy for laryngeal squamous cell carcinoma (SCC). The necessity of routine dissection at level IV has recently been questioned. The purpose of this study was to find the incidence of level IV metastases in patients with transglottic and supraglottic SCC who underwent neck dissections. Methods. The charts of 71 suitable patients were reviewed. Forty-two had supraglottic primary cancers, and 29 had transglottic primary tumors. Levels II-IV had been removed in them all, and their neck specimens were marked according to the levels of the neck. The surgical specimens were pathologically diagnosed. Results. Of 43 patients who underwent elective lateral neck dissection, the only one (2.3%) with level IV metastases also showed metastases at level II. Nine (32%) of the other 28 patients with clinical adenopathy had level IV metastases. Conclusions. Dissection of level IV as part of a therapeutic neck dissection for supraglottic and transglottic SCC is recommended for patients with clinically enlarged lymph nodes, but its necessity in the absence of detectable adenopathy is challenged.

Original languageEnglish
Pages (from-to)309-312
Number of pages4
JournalHead and Neck
Issue number4
StatePublished - Apr 2004
Externally publishedYes


  • Laryngeal cancer
  • Level IV lymph-node metastases
  • SCC


Dive into the research topics of 'Routine inclusion of level IV in neck dissection for squamous cell carcinoma of the larynx: Is it justified?'. Together they form a unique fingerprint.

Cite this