TY - JOUR
T1 - Role of the pulvinar-lateral posterior nucleus complex in turning behavior
AU - Motles, E.
AU - Ely, Y.
AU - Elazar, Z.
PY - 1980
Y1 - 1980
N2 - The behavioral response to electrical stimulation of the pulvinar-lateral posterior complex (P-LP) was studied in 11 adult cats with chronically implanted electrodes. The EEG of P-LP, caudate nucleus, superior colliculus, dorsal hippocampus and cerebral cortex was recorded during the stimulation sessions. Three cats had a cannula implanted in one P-LP through which drugs were microinjected. Threshold currents evoked contralateral head turning and conjugate eye deviation, and suprathreshold currents induced contralateral circling. Ninety-four percent of 456 stimulations in P-LP elicited contralateral head movements. P-LP EEG did not differ from controls during head turning induced by threshold currents, but it was desynchronized with slightly suprathreshold currents and occasionally showed after-discharges, concomitant with circling, with higher currents. Microinjections of ACh, KCl (25%), and penicillin into P-LP also induced contralateral circling, which was usually followed by a generalized epileptic seizure. This would support the postulate that the behavioral responses observed through electrical stimulation were mediated by synaptic activities within the P-LP. These results indicate that P-LP is involved in turning and circling behavior.
AB - The behavioral response to electrical stimulation of the pulvinar-lateral posterior complex (P-LP) was studied in 11 adult cats with chronically implanted electrodes. The EEG of P-LP, caudate nucleus, superior colliculus, dorsal hippocampus and cerebral cortex was recorded during the stimulation sessions. Three cats had a cannula implanted in one P-LP through which drugs were microinjected. Threshold currents evoked contralateral head turning and conjugate eye deviation, and suprathreshold currents induced contralateral circling. Ninety-four percent of 456 stimulations in P-LP elicited contralateral head movements. P-LP EEG did not differ from controls during head turning induced by threshold currents, but it was desynchronized with slightly suprathreshold currents and occasionally showed after-discharges, concomitant with circling, with higher currents. Microinjections of ACh, KCl (25%), and penicillin into P-LP also induced contralateral circling, which was usually followed by a generalized epileptic seizure. This would support the postulate that the behavioral responses observed through electrical stimulation were mediated by synaptic activities within the P-LP. These results indicate that P-LP is involved in turning and circling behavior.
KW - Cats chronically implanted
KW - Contralateral circling
KW - Contralateral head turning
KW - EEG behavioral correlates
KW - Electrical stimulation
KW - Pulvinar-LP complex
UR - http://www.scopus.com/inward/record.url?scp=0019191676&partnerID=8YFLogxK
U2 - 10.1016/0031-9384(80)90312-1
DO - 10.1016/0031-9384(80)90312-1
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AN - SCOPUS:0019191676
SN - 0031-9384
VL - 25
SP - 921
EP - 929
JO - Physiology and Behavior
JF - Physiology and Behavior
IS - 6
ER -