Role of perioperative antibiotic treatment in parotid gland surgery

Yotam Shkedy, Uri Alkan, Benjamin R. Roman, Ohad Hilly, Raphael Feinmesser, Gideon Bachar, Aviram Mizrachi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Background The value of routine prophylactic antibiotic treatment in parotid gland surgery remains undetermined. Methods A retrospective analysis was conducted of all patients who underwent parotidectomy at a university-affiliated tertiary care center between 1992 and 2009. Patients with insufficient data, specifically regarding postoperative complications and antibiotic administration were excluded from the study cohort. Results A total of 593 patients underwent parotidectomy during the study period. After exclusion, 464 patients were eligible for the study. Perioperative antibiotic treatment was given to 206 patients (45%). There was no difference in wound infection rates between patients who received perioperative antibiotic therapy and those who did not (p =.168). Multivariate analysis showed that female sex, neck dissection, and drain output >50 cc/24 hours were predictive of postoperative wound infection. Conclusion Routine prophylactic antibiotic treatment has no role in parotid gland surgery. Perioperative antibiotic treatment is recommended for patients undergoing extensive parotid gland surgery with neck dissection.

Original languageEnglish
Pages (from-to)E1876-E1880
JournalHead and Neck
StatePublished - 1 Apr 2016


FundersFunder number
National Cancer InstituteP30CA008748


    • drain
    • parotid gland
    • parotidectomy
    • perioperative antibiotic treatment
    • wound infection


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