Role of fibrinolysis in excessive menstrual bleeding (Hebrew)

A. Bar Am, R. Toaff, M. Hertzberg

Research output: Contribution to journalArticlepeer-review


In 18 women suffering from excessive menstrual bleeding unrelated to organic conditions, a therapeutic trial with the antifibrinolytic agent aminomethyl cyclohexane carboxylic acid was carried out. The menstrual blood loss was measured spectrophotometrically in 65 treated and 60 untreated cycles. A standard oral daily dose of 3 g reduced blood loss from an average of 119.5±49.3 ml/cycle to 54.2±16.7 ml/cycle and duration of menstruation from 7.61±1.7 days to 4.61±0.8 days. Side effects were infrequent and not serious. The favorable results obtained by antifibrinolytic treatment support the view that local fibrinolysis plays a definite role in functional menorrhagia.

Original languageEnglish
Pages (from-to)162-164+204
Issue number4
StatePublished - 1976
Externally publishedYes


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