TY - JOUR
T1 - Role of cytokines in heart failure
AU - Blum, A.
AU - Miller, H.
PY - 1998
Y1 - 1998
N2 - Heart failure is a complex neurohumoral and inflammatory syndrome. Studies have shown that proinflammatory cytokines (interleukin-1, interleukin-2, interleukin-6, and tumor necrosis factor) are involved in cardiac depression and in the complex syndrome of heart failure. Understanding the involvement of these cytokines may enable us to reverse cardiac depression and heart failure with the use of monoclonal antibodies directed against specific cytokines that may block the downhill progression of heart failure.
AB - Heart failure is a complex neurohumoral and inflammatory syndrome. Studies have shown that proinflammatory cytokines (interleukin-1, interleukin-2, interleukin-6, and tumor necrosis factor) are involved in cardiac depression and in the complex syndrome of heart failure. Understanding the involvement of these cytokines may enable us to reverse cardiac depression and heart failure with the use of monoclonal antibodies directed against specific cytokines that may block the downhill progression of heart failure.
UR - http://www.scopus.com/inward/record.url?scp=0031935393&partnerID=8YFLogxK
U2 - 10.1016/S0002-8703(98)70080-8
DO - 10.1016/S0002-8703(98)70080-8
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AN - SCOPUS:0031935393
SN - 0002-8703
VL - 135
SP - 181
EP - 186
JO - American Heart Journal
JF - American Heart Journal
IS - 2 I
ER -