Abstract
Factor FXIII (FXIII) is a plasma transglutaminase that catalyzes the cross link formation between fibrin chains to stabilize the clot. Beside it s function in hemostasis FXIII has a role in wound healing and embryo implantation - processes that involve angiogenesis. In this review we discuss the role of FXIII in angiogenesis and the molecular mechanisms underlying its pro-angiogenic effect. In addition, FXIII role in wound repair is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | P162-P165 |
| Journal | Pathophysiology of Haemostasis and Thrombosis |
| Volume | 35 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - May 2006 |
| Externally published | Yes |
Keywords
- Angiogenesis
- Factor FXIII
- Wound repair