Robust polytopic analysis of the feedback-control of Glycolysis in yeasts via some system norms

Eli Gershon, Uri Shaked, Liron Itzhaki

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper we consider a well studied model of Glycolysis in yeast cells, leading from Glucose to the end product Ethanol, via a minimal nine steps mechanism. We first linearize each step in the pathway around a given set point and we then assemble the (originally nonlinear) system as a linear system subject to various polytopic uncertainties. We study the effect of the negative feedback-loop that is internally exerted on the system. We then probe the sensitivity of the system to variations in certain variables in order to asses the possible optimality of the system in the H 2, H and the L 2 - L 2, L 2 - L 2 senses.

Original languageEnglish
Title of host publication2012 20th Mediterranean Conference on Control and Automation, MED 2012 - Conference Proceedings
Pages176-181
Number of pages6
DOIs
StatePublished - 2012
Event2012 20th Mediterranean Conference on Control and Automation, MED 2012 - Barcelona, Spain
Duration: 3 Jul 20126 Jul 2012

Publication series

Name2012 20th Mediterranean Conference on Control and Automation, MED 2012 - Conference Proceedings

Conference

Conference2012 20th Mediterranean Conference on Control and Automation, MED 2012
Country/TerritorySpain
CityBarcelona
Period3/07/126/07/12

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