Risk of Infections with Biological Agents

Uri Kopylov; Waqqas Afif

doi:10.1016/j.gtc.2014.05.001

Risk of Infections with Biological Agents

Uri Kopylov, Waqqas Afif^*

^*Corresponding author for this work

McGill University

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

An increasing proportion of patients with inflammatory bowel disease (IBD) are treated with biological medications. The risk of infectious complications remains a significant concern in patients treated with biologics. Treatment with biological agents in IBD is generally safe, but there may be an increased risk of certain opportunistic infections. Some of the infectious risks are class specific, whereas others are a common concern for all biologics. A careful screening, surveillance, and immunization program, in accordance with available guidelines, is important to minimize any risk of infectious complications.

Original language	English
Pages (from-to)	509-524
Number of pages	16
Journal	Gastroenterology Clinics of North America
Volume	43
Issue number	3
DOIs	https://doi.org/10.1016/j.gtc.2014.05.001
State	Published - Sep 2014
Externally published	Yes

Keywords

Anti-tumor necrosis factor α
Biologics
Infection
Inflammatory bowel disease
Opportunistic infections
Vaccinations

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.gtc.2014.05.001

Cite this

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title = "Risk of Infections with Biological Agents",

abstract = "An increasing proportion of patients with inflammatory bowel disease (IBD) are treated with biological medications. The risk of infectious complications remains a significant concern in patients treated with biologics. Treatment with biological agents in IBD is generally safe, but there may be an increased risk of certain opportunistic infections. Some of the infectious risks are class specific, whereas others are a common concern for all biologics. A careful screening, surveillance, and immunization program, in accordance with available guidelines, is important to minimize any risk of infectious complications.",

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KW - Infection

KW - Inflammatory bowel disease

KW - Opportunistic infections

KW - Vaccinations

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JF - Gastroenterology Clinics of North America

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Risk of Infections with Biological Agents

Abstract

Keywords

UN SDGs

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