TY - JOUR
T1 - Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.
AU - Kaye, K. S.
AU - Cosgrove, S.
AU - Harris, A.
AU - Eliopoulos, G. M.
AU - Carmeli, Y.
PY - 2001
Y1 - 2001
N2 - Among 477 patients with susceptible Enterobacter spp., 49 subsequently harbored third-generation cephalosporin-resistant Enterobacter spp. Broad-spectrum cephalosporins were independent risk factors for resistance (relative risk [OR] = 2.3, P = 0.01); quinolone therapy was protective (OR = 0.4, P = 0.03). There were trends toward decreased risk for resistance among patients receiving broad-spectrum cephalosporins and either aminoglycosides or imipenem. Of the patients receiving broad-spectrum cephalosporins, 19% developed resistance.
AB - Among 477 patients with susceptible Enterobacter spp., 49 subsequently harbored third-generation cephalosporin-resistant Enterobacter spp. Broad-spectrum cephalosporins were independent risk factors for resistance (relative risk [OR] = 2.3, P = 0.01); quinolone therapy was protective (OR = 0.4, P = 0.03). There were trends toward decreased risk for resistance among patients receiving broad-spectrum cephalosporins and either aminoglycosides or imipenem. Of the patients receiving broad-spectrum cephalosporins, 19% developed resistance.
UR - http://www.scopus.com/inward/record.url?scp=0034869795&partnerID=8YFLogxK
U2 - 10.1128/AAC.45.9.2628-2630.2001
DO - 10.1128/AAC.45.9.2628-2630.2001
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C2 - 11502540
AN - SCOPUS:0034869795
SN - 0066-4804
VL - 45
SP - 2628
EP - 2630
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 9
ER -
