Risk factors and mortality in patients with pneumonia and elevated troponin levels

Orly Efros*, Shelly Soffer, Avshalom Leibowitz, Alexander Fardman, Robert Klempfner, Eshcar Meisel, Grossman Ehud

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Pneumonia in hospitalized patients is associated with myocardial injury. In this study, we evaluated risk factors for myocardial injury in hospitalized patients with pneumonia and its prognostic value. We retrieved all patients who were hospitalized in internal medicine departments in a tertiary medical center between 2008 and 2019 with a diagnosis of pneumonia. From 2008 to 2019 a total of 20,683 adult patients were hospitalized in internal medicine wards in the Sheba Medical Center with a diagnosis of pneumonia, 8195 were tested for troponin levels, and 3207 had elevated levels. Risk factors for elevated troponin levels were age, prior diagnosis of ischemic heart disease, and elevated creatinine level upon admission. The in-hospital mortality and 1-year mortality rate were higher among patients who had elevated troponin levels when using a propensity score-based matched analysis. In conclusion, in hospitalized patients with pneumonia elevated troponin levels have a major impact on prognosis. Hence, troponin levels may be used as another tool of risk stratification for patients hospitalized with pneumonia.

Original languageEnglish
Article number21619
JournalScientific Reports
Volume10
Issue number1
DOIs
StatePublished - Dec 2020

Fingerprint

Dive into the research topics of 'Risk factors and mortality in patients with pneumonia and elevated troponin levels'. Together they form a unique fingerprint.

Cite this