Background: Lung cancer is the most common cause of cancer-related death. Objectives: To identify changing patterns of lung cancer and its histologic subtypes among different population groups in Israel over a 25 year period. Methods: Primary lung cancers, all types and all stages, diagnosed during 1990-2014 were recorded in the Israel National Cancer Registry database. Demographic information was retrieved from the National Population Register. Age-standardized rates for the different subgroups were calculated for each year. Joinpoint software was used to analyze trends in incidence. Results: We identified 42,672 lung cancer cases. The most common histology was adenocarcinoma (34%), followed by squamous cell carcinoma (19%), large cell/not-otherwise-specified (19%), other histologies (15%), and small cell lung cancer (11%). The adenocarcinoma incidence rose from 25.7% to 48.2% during the examined period. Large cell/not-otherwise-specified incidence peaked around 2005-2006 and declined after. Lung cancer incidence increased significantly for the population overall and specifically in Arab females, followed by Jewish females and by Arab males. Adenocarcinoma and small cell lung cancer increased in Jewish females and in Arab males. A younger age of diagnosis was seen In Arab compared to Jewish patients. Conclusions: Jewish females and Arab males and females living In Israel demonstrated a constant Increase In lung cancer Incidence, mostly In adenocarcinoma and small cell lung cancer Incidence. In addition, a younger age of diagnosis In Arabs was noted. Smoking reduction Interventions and screening should be Implemented In those populations.

Original languageEnglish
Pages (from-to)788-793
Number of pages6
JournalIsrael Medical Association Journal
Issue number12
StatePublished - 2021


  • Arab ethnicity
  • Female
  • Jewish ethnicity
  • Lung cancer
  • Registry analysis


Dive into the research topics of 'Rising incidence of lung cancer in Arab females, Jewish females, and Arab males from 1990 to 2014 in Israel'. Together they form a unique fingerprint.

Cite this