TY - JOUR
T1 - Ribosomal RNA cistron topography in Escherichia coli
AU - Osenholts, M.
AU - Yankofsky, S. A.
AU - Segal, E.
N1 - Funding Information:
We also wish to acknowledge the financial assistance provided by Tel Aviv University, which enabled us to carry out these studies.
PY - 1973/4/21
Y1 - 1973/4/21
N2 - Reported here are experiments showing that the multiple cistrons coding for the 23-S component of ribosomal RNA in Escherichia coli are not arranged as a single, contiguous block of genes. Instead, it is probable that a gene for 16-S ribosomal RNA is in close physical proximity to every individual 23-S ribosomal RNA locus. Moreover, interspersed between such 23-16-S gene pairs are regions of "spacer" DNA which are at least 2000 deoxyribonucleotide residues long. The possible significance of these findings is discussed.
AB - Reported here are experiments showing that the multiple cistrons coding for the 23-S component of ribosomal RNA in Escherichia coli are not arranged as a single, contiguous block of genes. Instead, it is probable that a gene for 16-S ribosomal RNA is in close physical proximity to every individual 23-S ribosomal RNA locus. Moreover, interspersed between such 23-16-S gene pairs are regions of "spacer" DNA which are at least 2000 deoxyribonucleotide residues long. The possible significance of these findings is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0015931880&partnerID=8YFLogxK
U2 - 10.1016/0005-2787(73)90125-1
DO - 10.1016/0005-2787(73)90125-1
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AN - SCOPUS:0015931880
SN - 0005-2787
VL - 308
SP - 88
EP - 100
JO - BBA Section Nucleic Acids And Protein Synthesis
JF - BBA Section Nucleic Acids And Protein Synthesis
IS - 1
ER -