Abstract
A broad spectrum of complications following COVID-19 has been documented in adults, including the new onset of autoimmune-related manifestations and rheumatic diseases. Numerous case studies, reviews, and clinical trials have been published regarding the relationship between COVID-19 and the generation of autoantibodies that may cause rheumatic and autoimmune diseases. The currently suggested pathophysiology that leads to the new onset of such disorders may include well-established mechanisms, such as molecular mimicry and hyperstimulation of the immune system. The prevailing conditions documented following COVID-19 include, yet are not limited to, rheumatoid arthritis, myositis, antiphospholipid antibodies, ITP, and thyroid dysfunction. This chapter will summarize the current documentation of the broad-spectrum rheumatic diseases and autoimmune manifestations mediated by a SARS-CoV-2 infection.
Original language | English |
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Title of host publication | Autoimmunity, COVID-19, Post-COVID19 Syndrome and COVID-19 Vaccination |
Publisher | Elsevier |
Pages | 437-449 |
Number of pages | 13 |
ISBN (Electronic) | 9780443185663 |
ISBN (Print) | 9780443185670 |
DOIs | |
State | Published - 1 Jan 2022 |
Keywords
- Antiphospholipid antibodies
- Autoimmune manifestations
- Autoimmunity
- COVID-19
- Guillain Barre syndrome
- Rheumatic disease
- Rheumatoid arthritis
- SARS-CoV-2