TY - JOUR
T1 - Retinal pigment epithelial tear following photodynamic therapy for choroidal neovascularization secondary to AMD
AU - Goldstein, Mich
AU - Heilweil, G.
AU - Barak, A.
AU - Loewenstein, A.
PY - 2005/12
Y1 - 2005/12
N2 - Purpose: To describe retinal pigment epithelial tear following photodynamic therapy (PDT) for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Design: Retrospective interventional case series. Methods: A retrospective study in an institutional practice. We describe seven cases of retinal pigment epithelial (RPE) tear, which developed in seven eyes of seven patients following PDT. All eyes had subfoveal CNV secondary to AMD. Results: Six eyes had occult subfoveal CNV, and one eye had recurrent classic subfoveal CNV. In five patients, the eye that developed the tear was the second eye, whereas the first eye had a disciform scar. In four eyes, the RPE tear developed after one PDT, in one eye the RPE tear developed after the second PDT, and in two eyes the RPE tear developed after the third PDT. In five of seven cases, there was a significant visual deterioration following the RPE tear. Conclusions: RPE tear is a complication that may occur following PDT in particular when the PDT is applied to an occult subfoveal CNV.
AB - Purpose: To describe retinal pigment epithelial tear following photodynamic therapy (PDT) for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Design: Retrospective interventional case series. Methods: A retrospective study in an institutional practice. We describe seven cases of retinal pigment epithelial (RPE) tear, which developed in seven eyes of seven patients following PDT. All eyes had subfoveal CNV secondary to AMD. Results: Six eyes had occult subfoveal CNV, and one eye had recurrent classic subfoveal CNV. In five patients, the eye that developed the tear was the second eye, whereas the first eye had a disciform scar. In four eyes, the RPE tear developed after one PDT, in one eye the RPE tear developed after the second PDT, and in two eyes the RPE tear developed after the third PDT. In five of seven cases, there was a significant visual deterioration following the RPE tear. Conclusions: RPE tear is a complication that may occur following PDT in particular when the PDT is applied to an occult subfoveal CNV.
KW - Choroidal neovascularization
KW - Photodynamic therapy
KW - Retinal pigment epithelial tear
UR - http://www.scopus.com/inward/record.url?scp=21844458843&partnerID=8YFLogxK
U2 - 10.1038/sj.eye.6701765
DO - 10.1038/sj.eye.6701765
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C2 - 15803179
AN - SCOPUS:21844458843
SN - 0950-222X
VL - 19
SP - 1315
EP - 1324
JO - Eye
JF - Eye
IS - 12
ER -