Reticulocyte analysis by flow cytometry and other techniques

Roger S. Riley, Jonathan M. Ben-Ezra, Ann Tidwell, Gina Romagnoli

Research output: Contribution to journalReview articlepeer-review


Enumeration of peripheral blood reticulocytes is an essential part ofthe diagnosis and management of anemic patients since the number of reticulocytes in the peripheral blood reflects the erythrocytic activity of the bone marrow. Reticulocyte enumeration using flow cytometric methodology is rapidly replacing the inaccurate imprecise manual counting technique used in the past. This article explores the pathophysiology of the reticulocyte the various means of counting reticulocytes and the diverse clinical applications of reticulocyte data.

Original languageEnglish
Pages (from-to)373-420
Number of pages48
JournalHematology/Oncology Clinics of North America
Issue number2
StatePublished - 2002
Externally publishedYes


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