TY - JOUR
T1 - Results of treatment of high risk childhood acute lymphoblastic leukemia
AU - Kende, George
AU - El‐Najjar, Khamis
AU - Ben‐Bassat, Isaac
AU - Neuman, Yoram
AU - Ballin, Ami
AU - Ramot, Bracha
PY - 1983
Y1 - 1983
N2 - Sixteen children with high risk acute lymphoblastic leukemia (ALL) who had one or more of the following risk factors: white cell count over 50 × 109/liter, mediastinal mass, age under 2 or over 10 years, extramedullary involvement, or T‐cell markers, were treated by a new protocol. All attained complete remission and 11 are still in their continuous first remission for 6‐53 months. High activity of adenosine deaminase (ADA) in the leukemic cells seems to be an independent risk factor, as in the high ADA level group, 4 out of 7 patients relapsed and died, while none of the 8 patients with low ADA levels relapsed or died.
AB - Sixteen children with high risk acute lymphoblastic leukemia (ALL) who had one or more of the following risk factors: white cell count over 50 × 109/liter, mediastinal mass, age under 2 or over 10 years, extramedullary involvement, or T‐cell markers, were treated by a new protocol. All attained complete remission and 11 are still in their continuous first remission for 6‐53 months. High activity of adenosine deaminase (ADA) in the leukemic cells seems to be an independent risk factor, as in the high ADA level group, 4 out of 7 patients relapsed and died, while none of the 8 patients with low ADA levels relapsed or died.
KW - adenosine deaminase(ADA)
KW - high risk acute lymphoblastic leukemia(ALL)
UR - http://www.scopus.com/inward/record.url?scp=0020581875&partnerID=8YFLogxK
U2 - 10.1002/mpo.2950110111
DO - 10.1002/mpo.2950110111
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0020581875
SN - 0098-1532
VL - 11
SP - 49
EP - 52
JO - Medical and Pediatric Oncology
JF - Medical and Pediatric Oncology
IS - 1
ER -
