TY - JOUR
T1 - Responses of human medial temporal lobe neurons are modulated by stimulus repetition
AU - Pedreira, Carlos
AU - Mormann, Florian
AU - Kraskov, Alexander
AU - Cerf, Moran
AU - Fried, Itzhak
AU - Koch, Christof
AU - Quiroga, Rodrigo Quian
PY - 2010/1
Y1 - 2010/1
N2 - Recent studies have reported the presence of single neurons with strong responses to visual inputs in the human medial temporal lobe. Here we show how repeated stimulus presentation - photos of celebrities and familiar individuals, landmark buildings, animals, and objects - modulates the firing rate of these cells: a consistent decrease in the neural activity was registered as images were repeatedly shown during experimental sessions. The effect of repeated stimulus presentation was not the same for all medial temporal lobe areas. These findings are consistent with the view that medial temporal lobe neurons link visual percepts to declarative memory.
AB - Recent studies have reported the presence of single neurons with strong responses to visual inputs in the human medial temporal lobe. Here we show how repeated stimulus presentation - photos of celebrities and familiar individuals, landmark buildings, animals, and objects - modulates the firing rate of these cells: a consistent decrease in the neural activity was registered as images were repeatedly shown during experimental sessions. The effect of repeated stimulus presentation was not the same for all medial temporal lobe areas. These findings are consistent with the view that medial temporal lobe neurons link visual percepts to declarative memory.
UR - http://www.scopus.com/inward/record.url?scp=74049151901&partnerID=8YFLogxK
U2 - 10.1152/jn.91323.2008
DO - 10.1152/jn.91323.2008
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C2 - 19864436
AN - SCOPUS:74049151901
SN - 0022-3077
VL - 103
SP - 97
EP - 107
JO - Journal of Neurophysiology
JF - Journal of Neurophysiology
IS - 1
ER -