Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Paul S. Aisen; Linda M. Bierer; Michael Davidson; Theresa M. Ryan; Ranti Kaminsky; Kenneth L. Davis

doi:10.1097/00019442-199300130-00009

Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Paul S. Aisen^*, Linda M. Bierer, Michael Davidson, Theresa M. Ryan, Ranti Kaminsky, Kenneth L. Davis

^*Corresponding author for this work

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

Abstract

A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.

Original language	English
Pages (from-to)	244-248
Number of pages	5
Journal	American Journal of Geriatric Psychiatry
Volume	1
Issue number	3
DOIs	https://doi.org/10.1097/00019442-199300130-00009
State	Published - 1993
Externally published	Yes

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title = "Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease",

abstract = "A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.",

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AU - Davis, Kenneth L.

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Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Abstract

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