TY - JOUR
T1 - Resistant arterial hypertension is associated with higher blood levels of complement C3 and C-reactive protein
AU - Magen, Eli
AU - Mishal, Joseph
AU - Paskin, Jana
AU - Glick, Zahava
AU - Yosefy, Chaim
AU - Kidon, Mona
AU - Schlesinger, Menachem
PY - 2008
Y1 - 2008
N2 - Arterial hypertension is associated with increased plasma levels of complement C3, C4, and C-reactive protein (CRP). The aim of the study was to compare these laboratory markers in patients with resistant arterial hypertension (RAH) and controlled arterial hypertension (CAH). Patients with RAH (n=34), those with CAH (n=34), and 26 normotensive controls were included. White blood cell count, erythrocyte sedimentation rates, and blood levels of complement components C3, C4, and high-sensitivity C-reactive protein (hs-CRP) were compared among the study groups. In the RAH group, serum C3 (183.9±47.5 mg/dL) and hs-CRP (6.9±5.8 mg/L) were higher than in the CAH group (C3, 123.1±42.3 mg/dL; P<.001, hs-CRP, 4.2±4.8; P=.021, respectively). Significant positive correlations between systolic blood pressure and C3 (r = 0.6481; P<.001) and hs-CRP (r=0.3968; P=.02) were observed in the RAH group. RAH is associated with higher blood levels of C3 and CRP.
AB - Arterial hypertension is associated with increased plasma levels of complement C3, C4, and C-reactive protein (CRP). The aim of the study was to compare these laboratory markers in patients with resistant arterial hypertension (RAH) and controlled arterial hypertension (CAH). Patients with RAH (n=34), those with CAH (n=34), and 26 normotensive controls were included. White blood cell count, erythrocyte sedimentation rates, and blood levels of complement components C3, C4, and high-sensitivity C-reactive protein (hs-CRP) were compared among the study groups. In the RAH group, serum C3 (183.9±47.5 mg/dL) and hs-CRP (6.9±5.8 mg/L) were higher than in the CAH group (C3, 123.1±42.3 mg/dL; P<.001, hs-CRP, 4.2±4.8; P=.021, respectively). Significant positive correlations between systolic blood pressure and C3 (r = 0.6481; P<.001) and hs-CRP (r=0.3968; P=.02) were observed in the RAH group. RAH is associated with higher blood levels of C3 and CRP.
UR - http://www.scopus.com/inward/record.url?scp=58249086869&partnerID=8YFLogxK
U2 - 10.1111/j.1751-7176.2008.00002.x
DO - 10.1111/j.1751-7176.2008.00002.x
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C2 - 18844762
AN - SCOPUS:58249086869
VL - 10
SP - 677
EP - 683
JO - Journal of Clinical Hypertension
JF - Journal of Clinical Hypertension
SN - 1524-6175
IS - 9
ER -
