Abstract
Hepatic artery infusion (HAI) is a locoregional treatment for liver tumors that delivers high-dose chemotherapy directly to the liver. This chapter focuses on reservoir-less ports for HAI, a technique that utilizes different chemotherapeutic agents compared to traditional HAI systems with pumps. The rationale for reservoir-less HAI, drugs used, and implantation techniques with both surgical and percutaneous approaches are described. Additionally, potential complications are addressed. The chapter concludes by discussing the application of reservoir-less port HAI for treatment of colorectal liver metastases (CRLM) and hepatocellular carcinoma (HCC). Studies have shown promising results for HAI with oxaliplatin for CRLM and HAI with FOLFOX for HCC, offering an alternative treatment option for these patients.
Original language | English |
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Title of host publication | Hepatic Arterial Infusion for Malignancy |
Publisher | Springer Science+Business Media |
Pages | 337-351 |
Number of pages | 15 |
ISBN (Electronic) | 9783031749353 |
ISBN (Print) | 9783031749346 |
DOIs | |
State | Published - 1 Jan 2025 |
Keywords
- Chemotherapy
- Colorectal liver metastases (CRLM)
- FOLFOX
- Hepatic artery infusion (HAI)
- Hepatocellular carcinoma (HCC)
- Oxaliplatin
- Reservoir-less port