Reservoir-Less Ports for Hepatic Arterial Infusion

Yael Berger, Gali Perl, Eran Sadot*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Hepatic artery infusion (HAI) is a locoregional treatment for liver tumors that delivers high-dose chemotherapy directly to the liver. This chapter focuses on reservoir-less ports for HAI, a technique that utilizes different chemotherapeutic agents compared to traditional HAI systems with pumps. The rationale for reservoir-less HAI, drugs used, and implantation techniques with both surgical and percutaneous approaches are described. Additionally, potential complications are addressed. The chapter concludes by discussing the application of reservoir-less port HAI for treatment of colorectal liver metastases (CRLM) and hepatocellular carcinoma (HCC). Studies have shown promising results for HAI with oxaliplatin for CRLM and HAI with FOLFOX for HCC, offering an alternative treatment option for these patients.

Original languageEnglish
Title of host publicationHepatic Arterial Infusion for Malignancy
PublisherSpringer Science+Business Media
Pages337-351
Number of pages15
ISBN (Electronic)9783031749353
ISBN (Print)9783031749346
DOIs
StatePublished - 1 Jan 2025

Keywords

  • Chemotherapy
  • Colorectal liver metastases (CRLM)
  • FOLFOX
  • Hepatic artery infusion (HAI)
  • Hepatocellular carcinoma (HCC)
  • Oxaliplatin
  • Reservoir-less port

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