Reproductive outcome following hysteroscopic adhesiolysis in Asherman's syndrome

Zvi Katz, Alon Ben-Arie, Samuel Lurie, Moshe Manor, Vaclav Insler

Research output: Contribution to journalArticlepeer-review

Abstract

Objective-To determine whether hysteroscopic adhesiolysis improves reproductive outcome in women with Asherman's syndrome and pregnancy failure. Subjects-Ninety consecutive women who had undergone hysteroscopic adhesiolysis of intrauterine adhesions during a 5-year period. Only women in whom at least two previous pregnancies had ended with either a spontaneous abortion or a premature delivery accompanied by fetal or neonatal mortality and a hysteroscopic diagnosis of intrauterine adhesions were enrolled. Results-Whereas pregnancy outcome prior to the operation was 18.3% term deliveries, 3.3% premature deliveries, 62.4% first-trimester abortions, and 16.0% late abortions, after hysteroscopic adhesiolysis pregnancy outcome was 68.6% term deliveries, 9.3% premature deliveries, 17.4% first-trimester abortions, and 4.7% late abortions. In women with two previous unsuccessful pregnancies, the operative success rate measured by delivering a healthy newborn improved from 18.3% preoperatively to 64% postoperatively. In women with three or more unsuccessful pregnancies the success rate improved from 18.3% to 75%. Successful outcome of adhesiolysis was observed in 61.9% of mild (stage I) and in 70.6% of moderate to severe cases (stages II and III) of intrauterine adhesions. Conclusion-Hysteroscopic adhesiolysis in women with Asherman's syndrome and poor reproductive performance contributes significantly to a successful reproductive outcome.

Original languageEnglish
Pages (from-to)462-465
Number of pages4
JournalInternational Journal of Fertility and Menopausal Studies
Volume41
Issue number5
StatePublished - 1996
Externally publishedYes

Keywords

  • adhesiolysis
  • Asherman's syndrome
  • hysteroscopic
  • reproductive outcome

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