The current study explored the relationship between non-suicidal self-injuries (NSSI) and students' perceptions of school among adolescents. A sample of 594 high-school students (54.4% male; mean age 14.96) completed validated self-reported measures. Students were divided into three groups: repetitive-NSSI (more than 6 occasions), occasional-NSSI (at least once but less than 6), and no-NSSI. Multi-nominal regression, controlling for gender, age, and depression symptoms, indicated that teachers’ psychological support, a sense of school belongingness, and negative perceptions of peer climate were significantly different between repetitive-NSSI and non-NSSI groups. These school-related factors should be considered as risk factors for NSSI behaviors.