TY - JOUR
T1 - Repeated noninfectious endophthalmitis after intravitreal administration of bevacizumab
T2 - A report of two cases
AU - Soudry, Shiri
AU - Loewenstein, Anat
AU - Moisseiev, Joseph
PY - 2010/6
Y1 - 2010/6
N2 - Purpose: To report on two patients with sterile endophthalmitis recurring twice after intravitreal bevacizumab injection. Methods: Two cases of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab are described, followed by a review of the literature. Results: Two patients presented with painful eyes and decreased vision associated with endophthalmitis several days after intravitreal bevacizumab injection. In both patients, vitreous specimens were sterile. The intraocular inflammation recurred after additional intravitreal injection of bevacizumab that was performed during subsequent follow-up. Conclusion: This is the first report of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab. Awareness of the possible association between bevacizumab administration and sterile endophthalmitis may be warranted.
AB - Purpose: To report on two patients with sterile endophthalmitis recurring twice after intravitreal bevacizumab injection. Methods: Two cases of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab are described, followed by a review of the literature. Results: Two patients presented with painful eyes and decreased vision associated with endophthalmitis several days after intravitreal bevacizumab injection. In both patients, vitreous specimens were sterile. The intraocular inflammation recurred after additional intravitreal injection of bevacizumab that was performed during subsequent follow-up. Conclusion: This is the first report of sterile intraocular inflammation recurring after repeated intravitreal injections of bevacizumab. Awareness of the possible association between bevacizumab administration and sterile endophthalmitis may be warranted.
KW - Age-related macular degeneration
KW - Intravitreal bevacizumab
KW - Repeat injection
KW - Sterile endophthalmitis
UR - http://www.scopus.com/inward/record.url?scp=79955075743&partnerID=8YFLogxK
U2 - 10.1097/ICB.0b013e3181a59d92
DO - 10.1097/ICB.0b013e3181a59d92
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AN - SCOPUS:79955075743
SN - 1935-1089
VL - 4
SP - 220
EP - 223
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
IS - 3
ER -