Repeated measurements of learned irrelevance by a novel within-subject paradigm in humans

Ariane Orosz, Joram Feldon, Gilad Gal, Andor Simon, Katja Cattapan-Ludewig

Research output: Contribution to journalArticlepeer-review

Abstract

Learned irrelevance (LIrr) refers to the retardation of classical conditioning following preexposure of the to-be-associated stimuli. Healthy volunteers have been tested on three occasions with a new LIrr paradigm avoiding methodological problems which afflict traditional paradigms. A significant LIrr effect was demonstrated on each occasion. Thus, the new paradigm enables repeated measurements of LIrr and might be useful in evaluating long-term effects of medication in psychiatric disorders exhibiting aberrant LIrr.

Original languageEnglish
Pages (from-to)1-3
Number of pages3
JournalBehavioural Brain Research
Volume180
Issue number1
DOIs
StatePublished - 4 Jun 2007
Externally publishedYes

Keywords

  • Attention
  • Information processing
  • Latent inhibition
  • Learned irrelevance
  • Repeated measurements
  • Schizophrenia
  • Within-subject design

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