Repeated measurements of learned irrelevance by a novel within-subject paradigm in humans

Ariane Orosz; Joram Feldon; Gilad Gal; Andor Simon; Katja Cattapan-Ludewig

doi:10.1016/j.bbr.2007.02.008

Repeated measurements of learned irrelevance by a novel within-subject paradigm in humans

Ariane Orosz^*, Joram Feldon, Gilad Gal, Andor Simon, Katja Cattapan-Ludewig

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Learned irrelevance (LIrr) refers to the retardation of classical conditioning following preexposure of the to-be-associated stimuli. Healthy volunteers have been tested on three occasions with a new LIrr paradigm avoiding methodological problems which afflict traditional paradigms. A significant LIrr effect was demonstrated on each occasion. Thus, the new paradigm enables repeated measurements of LIrr and might be useful in evaluating long-term effects of medication in psychiatric disorders exhibiting aberrant LIrr.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	Behavioural Brain Research
Volume	180
Issue number	1
DOIs	https://doi.org/10.1016/j.bbr.2007.02.008
State	Published - 4 Jun 2007
Externally published	Yes

Funding

Funders	Funder number
Katja Cattapan-Ludewig
National Alliance for Research on Schizophrenia and Depression

Keywords

Attention
Information processing
Latent inhibition
Learned irrelevance
Repeated measurements
Schizophrenia
Within-subject design

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10.1016/j.bbr.2007.02.008

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abstract = "Learned irrelevance (LIrr) refers to the retardation of classical conditioning following preexposure of the to-be-associated stimuli. Healthy volunteers have been tested on three occasions with a new LIrr paradigm avoiding methodological problems which afflict traditional paradigms. A significant LIrr effect was demonstrated on each occasion. Thus, the new paradigm enables repeated measurements of LIrr and might be useful in evaluating long-term effects of medication in psychiatric disorders exhibiting aberrant LIrr.",

keywords = "Attention, Information processing, Latent inhibition, Learned irrelevance, Repeated measurements, Schizophrenia, Within-subject design",

author = "Ariane Orosz and Joram Feldon and Gilad Gal and Andor Simon and Katja Cattapan-Ludewig",

note = "Funding Information: Financial support was provided by the Sarasota Opera Benefit through a 2003 NARSAD Young Investigators Award received by Katja Cattapan-Ludewig. The authors are specially grateful for the assistance of Pietro Ballinari in statistical matters.",

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AU - Cattapan-Ludewig, Katja

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Repeated measurements of learned irrelevance by a novel within-subject paradigm in humans

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