Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial)

Amir Halkin; Eve Aymong; David A. Cox; Roxana Mehran; Alexandra J. Lansky; Martin Fahy; Giora Weisz; Eulogio Garcia; James E. Tcheng; Cindy L. Grines; Gregg W. Stone

doi:10.1016/j.amjcard.2003.10.019

Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial)

Amir Halkin, Eve Aymong, David A. Cox, Roxana Mehran, Alexandra J. Lansky, Martin Fahy, Giora Weisz, Eulogio Garcia, James E. Tcheng, Cindy L. Grines, Gregg W. Stone

Clinical Departments

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Abstract

The importance of sustained patency of the infarct-related artery after primary percutaneous coronary intervention for acute myocardial infarction is controversial. We examined serial measures of left ventricular function and clinical outcomes in 280 patients with an initially occluded infarct artery in whom Thrombolysis In Myocardial Infarction trial grade 3 flow was achieved and routine follow-up angiography was performed 7 months after percutaneous cor-onary intervention. Reocclusion of the infarct artery was associated with decreased event-free survival, and the degree of restenosis was an independent predictor of the lack in improvement in left ventricular ejection fraction over time.

Original language	English
Pages (from-to)	349-353
Number of pages	5
Journal	American Journal of Cardiology
Volume	93
Issue number	3
DOIs	https://doi.org/10.1016/j.amjcard.2003.10.019
State	Published - 1 Feb 2004

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10.1016/j.amjcard.2003.10.019

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Halkin, A., Aymong, E., Cox, D. A., Mehran, R., Lansky, A. J., Fahy, M., Weisz, G., Garcia, E., Tcheng, J. E., Grines, C. L., & Stone, G. W. (2004). Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial). American Journal of Cardiology, 93(3), 349-353. https://doi.org/10.1016/j.amjcard.2003.10.019

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title = "Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial)",

abstract = "The importance of sustained patency of the infarct-related artery after primary percutaneous coronary intervention for acute myocardial infarction is controversial. We examined serial measures of left ventricular function and clinical outcomes in 280 patients with an initially occluded infarct artery in whom Thrombolysis In Myocardial Infarction trial grade 3 flow was achieved and routine follow-up angiography was performed 7 months after percutaneous cor-onary intervention. Reocclusion of the infarct artery was associated with decreased event-free survival, and the degree of restenosis was an independent predictor of the lack in improvement in left ventricular ejection fraction over time.",

author = "Amir Halkin and Eve Aymong and Cox, {David A.} and Roxana Mehran and Lansky, {Alexandra J.} and Martin Fahy and Giora Weisz and Eulogio Garcia and Tcheng, {James E.} and Grines, {Cindy L.} and Stone, {Gregg W.}",

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doi = "10.1016/j.amjcard.2003.10.019",

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Halkin, A, Aymong, E, Cox, DA, Mehran, R, Lansky, AJ, Fahy, M, Weisz, G, Garcia, E, Tcheng, JE, Grines, CL & Stone, GW 2004, 'Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial)', American Journal of Cardiology, vol. 93, no. 3, pp. 349-353. https://doi.org/10.1016/j.amjcard.2003.10.019

Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial). / Halkin, Amir; Aymong, Eve; Cox, David A. et al.
In: American Journal of Cardiology, Vol. 93, No. 3, 01.02.2004, p. 349-353.

Research output: Contribution to journal › Article › peer-review

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AU - Halkin, Amir

AU - Aymong, Eve

AU - Cox, David A.

AU - Mehran, Roxana

AU - Lansky, Alexandra J.

AU - Fahy, Martin

AU - Weisz, Giora

AU - Garcia, Eulogio

AU - Tcheng, James E.

AU - Grines, Cindy L.

AU - Stone, Gregg W.

PY - 2004/2/1

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N2 - The importance of sustained patency of the infarct-related artery after primary percutaneous coronary intervention for acute myocardial infarction is controversial. We examined serial measures of left ventricular function and clinical outcomes in 280 patients with an initially occluded infarct artery in whom Thrombolysis In Myocardial Infarction trial grade 3 flow was achieved and routine follow-up angiography was performed 7 months after percutaneous cor-onary intervention. Reocclusion of the infarct artery was associated with decreased event-free survival, and the degree of restenosis was an independent predictor of the lack in improvement in left ventricular ejection fraction over time.

AB - The importance of sustained patency of the infarct-related artery after primary percutaneous coronary intervention for acute myocardial infarction is controversial. We examined serial measures of left ventricular function and clinical outcomes in 280 patients with an initially occluded infarct artery in whom Thrombolysis In Myocardial Infarction trial grade 3 flow was achieved and routine follow-up angiography was performed 7 months after percutaneous cor-onary intervention. Reocclusion of the infarct artery was associated with decreased event-free survival, and the degree of restenosis was an independent predictor of the lack in improvement in left ventricular ejection fraction over time.

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Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC Trial)

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