Regenerative Endodontics: A Potential Solution for External Root Resorption (Case Series)

Margarita Yoshpe, Shmuel Einy, Nikita Ruparel, Shaul Lin, Arieh Y. Kaufman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Introduction: Regenerative endodontic procedures (REPs) are aimed to treat apical periodontitis and promote root maturation of immature necrotic teeth. However, REPs are not intended to be a primary indication for treating or arresting external root resorption (ERR). The purpose of this study was to describe REP treatment in the cessation of ERR. Methods: Four cases (5 teeth) of posttraumatic immature teeth diagnosed with necrotic pulp and apical periodontitis or chronic apical abscess were treated with REPs using plasma-rich fibrin as a scaffold. All the teeth showed ERR and have been followed up to 3 years. Results: This case series shows how REPs arrested ERR. In 3 of the cases, replacement resorption was arrested, thus avoiding complications of ankylosis and the need for decoronation. Conclusions: In addition to the known advantages of REPs, we show that REPs are a promising treatment modality for arresting ERR, warranting further clinical trials.

Original languageEnglish
Pages (from-to)192-199
Number of pages8
JournalJournal of Endodontics
Issue number2
StatePublished - Feb 2020


  • Ankylosis
  • dental trauma
  • external inflammatory root resorption
  • platelet-rich fibrin
  • regenerative endodontic procedure
  • replacement resorption


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