TY - JOUR
T1 - Reflectance confocal microscopy terminology glossary for nonmelanocytic skin lesions
T2 - A systematic review
AU - Navarrete-Dechent, Cristian
AU - DeRosa, Antonio P.
AU - Longo, Caterina
AU - Liopyris, Konstantinos
AU - Oliviero, Margaret
AU - Rabinovitz, Harold
AU - Marghoob, Ashfaq A.
AU - Halpern, Allan C.
AU - Pellacani, Giovanni
AU - Scope, Alon
AU - Jain, Manu
N1 - Publisher Copyright:
© 2018 American Academy of Dermatology, Inc.
PY - 2019/5
Y1 - 2019/5
N2 - Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.
AB - Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology for nonmelanocytic lesions (NMLs). Objective: To review published RCM terms for NMLs and identify likely synonymous terms. Methods: We conducted a systematic review of original research articles published up to August 19, 2017, adhering to Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. Two investigators gathered all published RCM terms used to describe basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and seborrheic keratosis/solar lentigo/lichen planus–like keratosis (SK/SL/LPLK). Synonymous terms were grouped on the basis of similarity in definition and histopathologic correlates. Results: The inclusion criteria was met by 31 studies. Average frequency of use per term was 1.6 (range 1-8). By grouping synonymous terms, the number of terms could be reduced from 58 to 18 for BCC, 58 to 36 for SCC, 23 to 12 for SK/SL/LPLK, and from 139 to 66 terms (52.5% reduction) in total. The frequency of term usage stratified by anatomic layer (suprabasal epidermis vs epidermal basal layer, dermoepidermal junction, and superficial dermis) was 27 (25.7%) versus 78 (74.2%) for BCC; 60 (64.5%) versus 33 (34.5%) for SCC, and 15 (45.4%) versus 18 (54.5%) for SK/SL/LPLK, respectively. Limitations: Articles that were not peer reviewed were excluded. Conclusion: Systematic review of published RCM terms provides the basis for future NMLs terminology consensus.
KW - actinic keratosis
KW - basal cell carcinoma
KW - diagnosis
KW - lichen planus-like keratosis
KW - melanoma
KW - nonmelanoma skin cancer
KW - reflectance confocal microscopy
KW - seborrheic keratosis
KW - squamous cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85063092068&partnerID=8YFLogxK
U2 - 10.1016/j.jaad.2018.12.007
DO - 10.1016/j.jaad.2018.12.007
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C2 - 30529706
AN - SCOPUS:85063092068
SN - 0190-9622
VL - 80
SP - 1414-1427.e3
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5
ER -