Reduced total complement haemolytic activity in schizophrenic patients

Marguerite Radwan, Jonathan Brandon, Yehuda Baruch, Mike Stawski, Sam Tyano, Abraham Weizman

Research output: Contribution to journalArticlepeer-review

Abstract

Serum concentrations of the third and fourth components of the complement system and total complement haemolytic activity were measured in 167 psychiatric patients. Total complement haemolytic activity was decreased in chronic schizophrenic patients as compared to healthy controls and bipolar patients. The relatively diminished total haemolytic activity was not attributable to drug treatment. It is not clear if the reduced total haemolytic activity is an epiphenomenon or related to the involvement of an autoimmune process in the pathophysiology of schizophrenia.

Original languageEnglish
Pages (from-to)315-318
Number of pages4
JournalPsychological Medicine
Volume23
Issue number2
DOIs
StatePublished - 1993

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