Reduced hospitalizations and death associated with influenza vaccination among patients with and without diabetes

Anthony D. Heymann*, Yonaton Shapiro, Gabriel Chodick, Varda Shalev, Ehud Kokia, Eyal Kramer, Joshua Shemer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


OBJECTIVE - To assess whether the influenza vaccination of community-dwelling, diabetic, elderly individuals is associated with reduced rates of hospitalization and death. RESEARCH DESIGN AND METHODS - In this outcome-research study, we compared mortality and hospitalization rates of 15,556 patients aged ≥65 years followed using a diabetes registry in a large health maintenance organization to that of 69,097 members not suffering from chronic disease who were considered as a reference group. The study outcomes included all-cause death and hospitalization in internal medicine or geriatric wards for any reason over winter and summer (control) periods. RESULTS - Vaccination rates were 48.8 and 42.0% among patients with diabetes and the reference population, respectively. Influenza vaccination was associated with a 12.3% reduction in hospitalization rates for patients with diabetes compared with 23.0% in the reference group (P = 0.08). The reduction in hospitalization rates was similar in both sexes among patients with diabetes. In addition, there was a significant reduction in mortality for the vaccinated group of patients with diabetes when compared with the nonvaccinated group except for female patients aged ≥85 years. CONCLUSIONS - The study results support the use of influenza vaccine among an elderly population. However, there does not appear to be an additional benefit for patients with diabetes.

Original languageEnglish
Pages (from-to)2581-2584
Number of pages4
JournalDiabetes Care
Issue number11
StatePublished - Nov 2004


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