Recurrent parotitis in selective IgA deficiency

Vered Shkalim*, Yehudit Monselise, Ronen Mosseri, Yaron Finkelstein, Ben Zion Garty

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Recurrent parotitis is an uncommon condition in children. In most cases the etiology is unknown, although the disease is occasionally associated with viral infections, autoimmune disorders and immunodeficiency. We describe, for the first time, a child with recurrent parotitis and isolated immunoglobulin A (IgA) deficiency, without autoimmune disease. As IgA is the main immunoglobulin secreted into the mucosal surfaces, including that of the respiratory and gastrointestinal tracts, and into the saliva, the lack of IgA may be involved in the pathogenesis of recurrent parotitis. We recommend that IgA and other immunoglobulins be tested in all cases of recurrent parotitis.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalPediatric Allergy and Immunology
Volume15
Issue number3
DOIs
StatePublished - Jun 2004

Keywords

  • Children
  • IgA deficiency
  • Immunodeficiency
  • Parotitis
  • Recurrent
  • Sjögren's syndrome

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