Skip to main navigation Skip to search Skip to main content

Recurrent Cardiovascular Events Despite Optimal LDL-Cholesterol Reduction: Therapeutic Challenges

  • Avishay Elis*
  • , Ela Giladi
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Despite the application of recommended guideline-driven therapies and optimal medical interventions, individuals with established cardiovascular disease remain susceptible to additional cardiovascular incidents, a phenomenon referred to as residual risk. Analyses of clinical trial data reveal significant residual cardiovascular risk in all treated patients, even in the setting of optimal LDL-C reduction, thus enforcing the need to revise the algorithms beyond focusing on LDL-C levels. We present a case that highlights the problem of residual risk upon well controlled LDL-C levels and provide insights for additional measures for residual risk reduction.

Original languageEnglish
Pages (from-to)724-728
Number of pages5
JournalIsrael Medical Association Journal
Volume26
StatePublished - Dec 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • anticoagulants
  • glucagon-like peptide-1 receptor agonist (GLP1 RA)
  • lipoprotein(a)
  • low-density lipoprotein cholesterol (LDL-C)
  • triglycerides

Fingerprint

Dive into the research topics of 'Recurrent Cardiovascular Events Despite Optimal LDL-Cholesterol Reduction: Therapeutic Challenges'. Together they form a unique fingerprint.

Cite this