Rectal ulcers: A rare gastrointestinal manifestation of systemic lupus erythematosus

Guy Amit, Ruth Stalnikowicz, Yehudit Ostrovsky, Diana Prus, Rami Eliakim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A patient with systemic lupus erythematosus (SLE) developed a rectal ulcer and sepsis from colonic bacteria. At that time she had no other clinical manifestations of SLE. Histopathologic examination of the biopsies taken from the ulcer found evidence of vasculitis. Treatment with high-dose systemic steroids healed the ulcer clinically and endoscopically, but symptoms recurred when steroids were tapered. The patient was referred for surgery. This is a rare but dangerous complication of SLE and can be the only clinical manifestation of the disease.

Original languageEnglish
Pages (from-to)200-202
Number of pages3
JournalJournal of Clinical Gastroenterology
Issue number2
StatePublished - Sep 1999
Externally publishedYes


  • Rectal ulcer
  • Systemic lupus erythematosus
  • Vasculitis


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