Reconstructing Denisovan Anatomy Using DNA Methylation Maps

David Gokhman*, Nadav Mishol, Marc de Manuel, David de Juan, Jonathan Shuqrun, Eran Meshorer, Tomas Marques-Bonet, Yoel Rak, Liran Carmel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

DNA methylation maps can be used to predict anatomical features in hominins and chimpanzees, allowing for reconstruction of a putative anatomical profile of the Denisovan, currently absent from the fossil record.

Original languageEnglish
Pages (from-to)180-192.e10
JournalCell
Volume179
Issue number1
DOIs
StatePublished - 19 Sep 2019

Funding

FundersFunder number
Clore Israel FoundationBFU2017-86471-P
MINECO/FEDERU01 MH106874
Shiran Bar
National Geographic SocietyHJ-111R-17
Generalitat de CatalunyaGRC 2017 SGR 880

    Keywords

    • Denisova
    • Neanderthal
    • aDNA
    • disease
    • jaw
    • loss of function
    • methylome
    • paleoepigenetics
    • paleogenomics
    • phenotype

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