Recommendations for Successful Training on Methods of Delivery of Biologics for Cardiac Regeneration. A Report of the International Society for Cardiovascular Translational Research

Nabil Dib, Philippe Menasche, Jozef J. Bartunek, Andreas M. Zeiher, Andre Terzic, Nicolas A. Chronos, Timothy D. Henry, Nicholas S. Peters, Francisco Fernández-Avilés, Magdi Yacoub, Timothy A. Sanborn, Anthony DeMaria, Richard A. Schatz, Doris A. Taylor, Shmuel Fuchs, Silviu Itescu, Leslie W. Miller, Jonathan H. Dinsmore, George D. Dangas, Jeffrey J. PopmaJennifer L. Hall, David R. Holmes

Research output: Contribution to journalReview articlepeer-review

77 Scopus citations

Abstract

The field of myocardial regeneration (angiogenesis and myogenesis) might prove to play an important role in the future management of cardiovascular disease. Stem cells are currently undergoing testing in Phase I and Phase II clinical trials. Methods of delivery will affect the outcome of such therapies, perhaps significantly. This document provides suggested guidance in 4 methods of delivery: endocardial, intracoronary, coronary sinus, and epicardial.

Original languageEnglish
Pages (from-to)265-275
Number of pages11
JournalJACC: Cardiovascular Interventions
Volume3
Issue number3
DOIs
StatePublished - Mar 2010

Funding

FundersFunder number
Ablation Frontiers Inc.
AstraZeneca Inc.
Bioheart Inc.
Cardio3 Biosciences
CardioPolymers Inc
CardioPolymers Inc.
Cardiovascular Biotherapeutics and Angioblast Systems, Inc.
Magnetecs Inc.
Philips Medical Systems
Sanofi Aventis Inc.
Thoratec Corp
Medtronic
CORDIS
Boston Scientific Corporation
Abbott Vascular
CORDIS

    Keywords

    • catheter
    • injection
    • myocardial regeneration
    • stem cells
    • training

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