Recent N-atom containing compounds from Indo-Pacific invertebrates

Yoel Kashman, Ashgan Bishara, Maurice Aknin

Research output: Contribution to journalReview articlepeer-review


A large variety of unique N-atom containing compounds (alkaloids) without terrestrial counterparts, have been isolated from marine invertebrates, mainly sponges and ascidians. Many of these compounds display interesting biological activities. In this report we present studies on nitrogenous compounds, isolated by our group during the last few years, from Indo-Pacific sponges, one ascidian and one gorgonian. The major part of the review deals with metabolites from the Madagascar sponge Fascaplysinopsis sp., namely, four groups of secondary metabolites, the salarins, tulearins, taumycins and tausalarins.

Original languageEnglish
Pages (from-to)2810-2836
Number of pages27
JournalMarine Drugs
Issue number11
StatePublished - Nov 2010


  • Fascaplysinopsis sp.
  • Heterocycles
  • Leukemia cells
  • Marine invertebrates
  • Nitrogenous macrolide


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