TY - JOUR
T1 - Real-Life Barriers to Diagnosis of Early Mycosis Fungoides
T2 - An International Expert Panel Discussion
AU - Hodak, Emmilia
AU - Geskin, Larisa
AU - Guenova, Emmanuella
AU - Ortiz-Romero, Pablo L.
AU - Willemze, Rein
AU - Zheng, Jie
AU - Cowan, Richard
AU - Foss, Francine
AU - Mangas, Cristina
AU - Querfeld, Christiane
N1 - Publisher Copyright:
© 2022, The Author(s).
PY - 2023/1
Y1 - 2023/1
N2 - Mycosis fungoides (MF) is a rare, primary cutaneous T-cell lymphoma that is challenging to diagnose due to its heterogeneous clinical presentation and complex histology. The subtlety of the initial clinical appearance of MF can result in diagnostic delays and hesitancy to refer suspected cases to specialist clinics. An unmet need remains for greater awareness and education. Therefore, an international expert panel of dermatologists, oncologists, hematologists, and dermatopathologists convened to discuss and identify barriers to early and accurate MF diagnosis that could guide clinicians toward making a correct diagnosis. Confirmation of MF requires accurate assessment of symptoms and clinical signs, and subsequent correlation with dermatopathological findings. This review summarizes the expert panel’s guidance, based on the literature and real-life experience, for dermatologists to help include MF in their list of differential diagnoses, along with simple clinical and histopathologic checklists that may help clinicians to suspect and identify potential MF lesions and reduce diagnostic delays.
AB - Mycosis fungoides (MF) is a rare, primary cutaneous T-cell lymphoma that is challenging to diagnose due to its heterogeneous clinical presentation and complex histology. The subtlety of the initial clinical appearance of MF can result in diagnostic delays and hesitancy to refer suspected cases to specialist clinics. An unmet need remains for greater awareness and education. Therefore, an international expert panel of dermatologists, oncologists, hematologists, and dermatopathologists convened to discuss and identify barriers to early and accurate MF diagnosis that could guide clinicians toward making a correct diagnosis. Confirmation of MF requires accurate assessment of symptoms and clinical signs, and subsequent correlation with dermatopathological findings. This review summarizes the expert panel’s guidance, based on the literature and real-life experience, for dermatologists to help include MF in their list of differential diagnoses, along with simple clinical and histopathologic checklists that may help clinicians to suspect and identify potential MF lesions and reduce diagnostic delays.
UR - http://www.scopus.com/inward/record.url?scp=85142373576&partnerID=8YFLogxK
U2 - 10.1007/s40257-022-00732-w
DO - 10.1007/s40257-022-00732-w
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C2 - 36399227
AN - SCOPUS:85142373576
SN - 1175-0561
VL - 24
SP - 5
EP - 14
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 1
ER -