Reactivity of IgM-rheumatoid factors of human, feline and bovine sera

  • M. Waron
  • , Z. Trainin
  • , Anita Gluckman
  • , Hanna Ungar-Waron*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The reactions of IgM-rheumatoid factors (IgM-RFs) from human, feline and bovine sera were examined with their homologous monomeric IgGs and with IgGs of other species. Cross-reactivities with IgGs of other species were observed in each separate system. By the use of an enzyme-linked immunosorbent assay (ELISA), measurable differences in reactivities were obtained. The results suggest that IgM-RFs of human and feline origin recognize a similar determinant on the Fc region of IgG. A different moiety on the latter molecule appears to be involved in the reactivity of bovine IgM-RF.

Original languageEnglish
Pages (from-to)487-490
Number of pages4
JournalJournal of Comparative Pathology
Volume97
Issue number4
DOIs
StatePublished - Jul 1987
Externally publishedYes

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