TY - JOUR
T1 - Reactive oxygen species in the process of labor
AU - Yaacobi, N.
AU - Ohel, G.
AU - Hochman, A.
PY - 1999/11
Y1 - 1999/11
N2 - Levels of thiobarbituric acid reactive substances (TBARS), an indicative parameter for oxidative damage, were measured in maternal and cord arterial and venous bloods, and compared between abdominal and vaginal deliveries. Spontaneous labor resulting in either vaginal or emergency abdominal deliveries was associated with a statistically significant higher levels of TBARS in cord artery compared to cord vein and maternal blood (p < 0.05). The results support a role of reactive oxygen species in the initiation of labor, possibly through their effect on prostaglandin metabolism. Alternatively, this may be a marker of fetal oxidative stress, secondary to the process of labor.
AB - Levels of thiobarbituric acid reactive substances (TBARS), an indicative parameter for oxidative damage, were measured in maternal and cord arterial and venous bloods, and compared between abdominal and vaginal deliveries. Spontaneous labor resulting in either vaginal or emergency abdominal deliveries was associated with a statistically significant higher levels of TBARS in cord artery compared to cord vein and maternal blood (p < 0.05). The results support a role of reactive oxygen species in the initiation of labor, possibly through their effect on prostaglandin metabolism. Alternatively, this may be a marker of fetal oxidative stress, secondary to the process of labor.
KW - Initiation of labor
KW - Lipid peroxidation
KW - Prostaglandin
KW - Reactive oxygen species
KW - Umbilical cord blood
UR - http://www.scopus.com/inward/record.url?scp=0033397296&partnerID=8YFLogxK
U2 - 10.1007/s004040050255
DO - 10.1007/s004040050255
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0033397296
SN - 0932-0067
VL - 263
SP - 23
EP - 24
JO - Archives of Gynecology and Obstetrics
JF - Archives of Gynecology and Obstetrics
IS - 1-2
ER -