TY - JOUR
T1 - Rapid Detection of Carbapenemase-producing Enterobacteriaceae from Blood Culture Bottles of Known CPE Carriers
T2 - Real-world Experience
AU - Kriger, Or
AU - Shatzman-Steuerman, Rachel
AU - Smollan, Gillian
AU - Belausov, Natasha
AU - Sarkisian, Gayane
AU - Amit, Sharon
N1 - Publisher Copyright:
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - We used a rapid antigen test for the detection of carbapenemases directly from positive blood culture bottles of pediatric hemato-oncologic patients, known carriers of carbapenemase-producing enterobacteriaceae. Resistance mechanism was detected within 15 minutes of observing Gram-negative bacilli from a positive bottle, leading to treatment modification. This simple-to-use, inexpensive assay shortens the interval between empiric to tailored antimicrobial therapy.
AB - We used a rapid antigen test for the detection of carbapenemases directly from positive blood culture bottles of pediatric hemato-oncologic patients, known carriers of carbapenemase-producing enterobacteriaceae. Resistance mechanism was detected within 15 minutes of observing Gram-negative bacilli from a positive bottle, leading to treatment modification. This simple-to-use, inexpensive assay shortens the interval between empiric to tailored antimicrobial therapy.
KW - CPE
KW - bacteremia
KW - rapid detection
UR - http://www.scopus.com/inward/record.url?scp=85122066048&partnerID=8YFLogxK
U2 - 10.1097/INF.0000000000003311
DO - 10.1097/INF.0000000000003311
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C2 - 34471083
AN - SCOPUS:85122066048
SN - 0891-3668
VL - 41
SP - 45
EP - 47
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 1
ER -