Rapid Detection of Carbapenemase-producing Enterobacteriaceae from Blood Culture Bottles of Known CPE Carriers: Real-world Experience

Or Kriger*, Rachel Shatzman-Steuerman, Gillian Smollan, Natasha Belausov, Gayane Sarkisian, Sharon Amit

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We used a rapid antigen test for the detection of carbapenemases directly from positive blood culture bottles of pediatric hemato-oncologic patients, known carriers of carbapenemase-producing enterobacteriaceae. Resistance mechanism was detected within 15 minutes of observing Gram-negative bacilli from a positive bottle, leading to treatment modification. This simple-to-use, inexpensive assay shortens the interval between empiric to tailored antimicrobial therapy.

Original languageEnglish
Pages (from-to)45-47
Number of pages3
JournalPediatric Infectious Disease Journal
Volume41
Issue number1
DOIs
StatePublished - 1 Jan 2022
Externally publishedYes

Keywords

  • CPE
  • bacteremia
  • rapid detection

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