TY - JOUR
T1 - Randomized clinical trials in advanced and metastatic colorectal carcinoma
AU - D'Angelica, Michael I.
AU - Shoup, Margo C.
AU - Nissan, Aviram
PY - 2002
Y1 - 2002
N2 - The treatment of advanced colorectal cancer has long been a dilemna for clinicians. After many years of therapy limited to 5-fluorouracil (5-FU)-based chemotherapy, a number of new discoveries have significantly advanced this field in the last decade. The advent of irinotecan has given us hope for a second line chemotherapeutic agent and a possible new combination for first line chemotherapy.
AB - The treatment of advanced colorectal cancer has long been a dilemna for clinicians. After many years of therapy limited to 5-fluorouracil (5-FU)-based chemotherapy, a number of new discoveries have significantly advanced this field in the last decade. The advent of irinotecan has given us hope for a second line chemotherapeutic agent and a possible new combination for first line chemotherapy.
UR - http://www.scopus.com/inward/record.url?scp=0036135120&partnerID=8YFLogxK
U2 - 10.1016/S1055-3207(03)00080-2
DO - 10.1016/S1055-3207(03)00080-2
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C2 - 11928799
AN - SCOPUS:0036135120
SN - 1055-3207
VL - 11
SP - 173
EP - 191
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 1
ER -
