Radiologic features of gastric outlet obstruction in infants after long-term prostaglandin administration

P. Babyn, N. Peled, D. Manson, O. Dagan, M. M. Silver, G. Koren

Research output: Contribution to journalArticlepeer-review

Abstract

Long-term prostaglandin (PG) therapy has recently been associated with gastric mucosal hyperplasia. We reviewed the clinical and radiologic (especially sonographic) records of eight patients with complex congenital heart disease who were on PG therapy. Feeding problems, vomiting, and abdominal distension were present in six patients. Barium meal revealed antral narrowing in three patients, suggestive of hypertrophic pyloric stenosis in two. Sonography showed a variable degree of increased gastric mucosal lobulation often accompanied by a marked polypoid or lobular appearance. Cortical hyperostosis related to PG therapy was seen in three patients. PG-associated gastric mucosal hyperplasia can cause feeding problems and pronounced gastric lobulation.

Original languageEnglish
Pages (from-to)41-43
Number of pages3
JournalPediatric Radiology
Volume25
Issue number1
DOIs
StatePublished - Feb 1995
Externally publishedYes

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