Radioimmunodetection of tumors with monoclonal antiplacental ferritin antibody: Preliminary results

  • C. Moroz
  • , Z. Lantsberg
  • , O. Sela
  • , Y. Cohen
  • , J. Khodadadi
  • , J. Goldstein
  • , M. R. Quastel
  • , Y. Shoenfeld*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Two mouse monoclonal antiferritin antibodies were employed to detect tumors. In the first case a solitary hepatoma was defined, while in the second one, mediastinal metastases of breast cancer were detected. In both cases serum ferritin levels were raised. The availability of monoclonal antiferritin antibodies offers certain advantages over polyclonal antibodies (ease of production, purification and reproducibility). These antiferritin antibodies may be found useful in diagnosis and therapy of certain tumors.

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalOncology (Switzerland)
Volume46
Issue number1
DOIs
StatePublished - 1989

Keywords

  • Antiferritin antibodies
  • Breast carcinoma
  • Ferritin
  • Hepatoma

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