Quinine alone versus quinine plus a pyrimethamine-sulfadoxine combination in the treatment of Plasmodium faliciparum cerebral malaria

Y. Naparstek, D. Weiler-Ravell, J. Shemer, D. Englehard, J. Sack, D. T. Spira, J. Adler

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).

Original languageEnglish
Pages (from-to)1342-1343
Number of pages2
JournalUnknown Journal
Volume30
Issue number6
DOIs
StatePublished - 1981
Externally publishedYes

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