Quinine alone versus quinine plus a pyrimethamine-sulfadoxine combination in the treatment of Plasmodium faliciparum cerebral malaria

Y. Naparstek; D. Weiler-Ravell; J. Shemer; D. Englehard; J. Sack; D. T. Spira; J. Adler

doi:10.4269/ajtmh.1981.30.1342

Quinine alone versus quinine plus a pyrimethamine-sulfadoxine combination in the treatment of Plasmodium faliciparum cerebral malaria

Y. Naparstek, D. Weiler-Ravell, J. Shemer, D. Englehard, J. Sack, D. T. Spira, J. Adler

Research output: Contribution to journal › Article › peer-review

Abstract

Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).

Original language	English
Pages (from-to)	1342-1343
Number of pages	2
Journal	Unknown Journal
Volume	30
Issue number	6
DOIs	https://doi.org/10.4269/ajtmh.1981.30.1342
State	Published - 1981
Externally published	Yes

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10.4269/ajtmh.1981.30.1342

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abstract = "Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).",

author = "Y. Naparstek and D. Weiler-Ravell and J. Shemer and D. Englehard and J. Sack and Spira, {D. T.} and J. Adler",

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doi = "10.4269/ajtmh.1981.30.1342",

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T1 - Quinine alone versus quinine plus a pyrimethamine-sulfadoxine combination in the treatment of Plasmodium faliciparum cerebral malaria

AU - Naparstek, Y.

AU - Weiler-Ravell, D.

AU - Shemer, J.

AU - Englehard, D.

AU - Sack, J.

AU - Spira, D. T.

AU - Adler, J.

PY - 1981

Y1 - 1981

N2 - Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).

AB - Fifty-two patients with severe chloroquine resistant Plasmodium falciparum malaria were treated in a randomized double blind study with either quinine and a single dose of pyrimethamine-sulfadoxine (Fansidar) or quinine alone. Although no statistically significant differences were observed, the 25 patients who received both drugs responded faster and had a more favorable outcome (no deaths) when compared to the 27 who received quinine alone (2 deaths).

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U2 - 10.4269/ajtmh.1981.30.1342

DO - 10.4269/ajtmh.1981.30.1342

M3 - מאמר

AN - SCOPUS:0019857416

VL - 30

SP - 1342

EP - 1343

JO - Unknown Journal

JF - Unknown Journal

IS - 6

ER -

Quinine alone versus quinine plus a pyrimethamine-sulfadoxine combination in the treatment of Plasmodium faliciparum cerebral malaria

Abstract

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