Quality of life after mandibulectomy: the impact of the resected subsite

A. Warshavsky, D. M. Fliss, G. Frenkel, A. Kupershmidt, N. Moav, R. Rosen, M. Sechter, U. Shapira, S. Abu-Ghanem, M. Yehuda, A. Zaretski, R. Yanko-Arzi, V. Reiser, G. Horowitz

Research output: Contribution to journalArticlepeer-review


The purpose of this study was to identify the factors that impact the quality of life (QOL) scores of patients undergoing mandibulectomy. All patients with a diagnosis of an oral cavity neoplasm involving the mandible who underwent a mandibulectomy between January 1, 2000 and December 31, 2015 and completed a University of Washington QOL questionnaire (UW-QOL) were included in the study. Fifty-eight patients fulfilled all inclusion criteria and completed the UW-QOL questionnaire. Forty patients (69%) underwent a segmental mandibulectomy and 18 patients underwent a marginal mandibulectomy. Forty-eight patients (82.7%) had a free flap reconstruction. There was no significant difference in the QOL scores between patients who underwent a marginal or a segmental mandibulectomy. In contrast, patients who underwent symphysial resection reported significantly worse scores in various domains compared to patients with body or ramus segmental mandibulectomy. Patients who underwent a segmental mandibulectomy that included the symphysis had worse outcomes in chewing, recreation, health-related and social QOL domains compared to those whose mandibulectomy did not include the symphysis.

Original languageEnglish
Pages (from-to)1273-1278
Number of pages6
JournalInternational Journal of Oral and Maxillofacial Surgery
Issue number10
StatePublished - Oct 2019
Externally publishedYes


  • mandibulectomy
  • quality of life
  • segmental
  • symphysis


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