Pupillary responses and blink reflex in myotonic dystrophy

Malvina Alon; Amos D. Korczyn

doi:10.1007/BF01824206

Pupillary responses and blink reflex in myotonic dystrophy

Malvina Alon, Amos D. Korczyn^*

^*Corresponding author for this work

Physiology Pharmacology

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We have studied pupillary responses to parasympathetic and sympathomimetic agents, pupillary cycle time and the electrophysiology of the blink reflex in 18 patients with myotonic dystrophy. The response of the iris to dilute pilocarpine and phenylephrine did not indicate pharmacologic supersensitivity. Pupillary cycle time was prolonged in nine of the 18 patients. Ipsilateral R₁ blink reflex latencies were normal in all cases, and bilateral R₂ were normal in 16 of the 18 patients. These results do not support either autonomic or brainstem dysfunction in the majority of patients with myotonic dystrophy. In 50% of the patients the results are compatible with smooth muscle involvement of the iris.

Original language	English
Pages (from-to)	17-19
Number of pages	3
Journal	Clinical Autonomic Research
Volume	2
Issue number	1
DOIs	https://doi.org/10.1007/BF01824206
State	Published - Feb 1992

Keywords

Blink reflex
Myotonic dystrophy
Pupil
Pupillary cycle time
Smooth muscle

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10.1007/BF01824206

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abstract = "We have studied pupillary responses to parasympathetic and sympathomimetic agents, pupillary cycle time and the electrophysiology of the blink reflex in 18 patients with myotonic dystrophy. The response of the iris to dilute pilocarpine and phenylephrine did not indicate pharmacologic supersensitivity. Pupillary cycle time was prolonged in nine of the 18 patients. Ipsilateral R1 blink reflex latencies were normal in all cases, and bilateral R2 were normal in 16 of the 18 patients. These results do not support either autonomic or brainstem dysfunction in the majority of patients with myotonic dystrophy. In 50% of the patients the results are compatible with smooth muscle involvement of the iris.",

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Pupillary responses and blink reflex in myotonic dystrophy

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