Pulsed photothermal radiometry of port-wine stains

Tom E. Milner*, J. S.M.D. Nelson, N. Tran, Abraham Katzir, Lars O. Svaasand, et.al.

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The application of pulsed photothermal radiometry (PPTR) diagnostics to characterize port wine stain (PWS) lesions is discussed. Influence of epidermal absorbance and PWS depth on the PPTR signal is analyzed using an in-vitro model of PWS skin consisting of multilayered collagen films. An instrument is constructed and used for patient and animal model PPTR measurements. When an infrared fiber is incorporated, the instrumentation facilitates convenient skin-site accessibility. Modulation of the PPTR signal and homodyne detection substantially improve the system signal-to-noise ratio over previous methods. Given the measured PPTR signal, an algorithm computes the initial temperature distribution in the PWS skin immediately after the laser pulse. The use and limitations of the algorithm are presented and discussed.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Society of Photo-Optical Instrumentation Engineers
Number of pages9
ISBN (Print)0819411094, 9780819411099
StatePublished - 1993
Externally publishedYes
EventLaser-Tissue Interaction IV - Los Angeles, CA, USA
Duration: 18 Jan 199320 Jan 1993

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


ConferenceLaser-Tissue Interaction IV
CityLos Angeles, CA, USA


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