Psoriatic spondyloarthropathy in men and women: A clinical, radiographic, and HLA study

D. D. Gladman, B. Brubacher, D. Buskila, P. Langevitz, V. T. Farewell

Research output: Contribution to journalArticlepeer-review

Abstract

Psoriatic spondyloarthropathy as defined by the presence of inflammatory back pain and stiffness, sacroiliitis on physical examination, radiographic evidence of grade ≥ 2 sacroiliitis, and classical or paramarginal syndesmophytes on spinal radiographs was identified in 82 women and 112 men followed at the Psoriatic Arthritis Clinic according to a standard protocol. A logistic regression analysis was performed to look for variables which discriminate between men and women with this condition. No differences in type of peripheral arthritis, degree of damage, or medication were noted between the two groups. However, there was some evidence for more advanced spondyloarthropathy in men. There were no differences in the frequency of HLA B27 or any of the psoriatic arthritis-related HLA antigens. Thus, there may be gender-related differences in the expression of psoriatic spondyloarthropathy, which are unrelated to HLA antigens.

Original languageEnglish
Pages (from-to)371-375
Number of pages5
JournalClinical and Investigative Medicine
Volume15
Issue number4
StatePublished - 1992
Externally publishedYes

Keywords

  • disease expression
  • psoriatic spondyloarthropathy

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