Pseudocholinesterase in obsessive-compulsive patients

Dov Aizenberg; Haggai Hermesh; Leon Karp; Hanan Munitz

doi:10.1016/0165-1781(89)90010-3

Pseudocholinesterase in obsessive-compulsive patients

Dov Aizenberg^*, Haggai Hermesh, Leon Karp, Hanan Munitz

^*Corresponding author for this work

Clinical Departments

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Levels of pseudocholinesterase (PsChe) were measured in 20 patients with obsessive-compulsive disorder (OCD) and 20 healthy volunteers. The OCD group had significantly higher PsChe serum activity than in their sex- and age-matched control group. Patients' scores on the Hamilton Rating Scale for Anxiety (HRS-A) and the Beck Depression Inventory (BDI) were not correlated with their PsChe levels. The results provide additional support for the observation of higher PsChe levels among anxiety-related psychiatric conditions. However, the relationships among anxiety, depression, and PsChe appear to be complex. The nature and implications of elevated PsChe levels are still unknown.

Original language	English
Pages (from-to)	65-69
Number of pages	5
Journal	Psychiatry Research
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/0165-1781(89)90010-3
State	Published - Jan 1989

Keywords

Pseudocholinesterase
anxiety
depression
obsessive-compulsive disorder

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10.1016/0165-1781(89)90010-3

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abstract = "Levels of pseudocholinesterase (PsChe) were measured in 20 patients with obsessive-compulsive disorder (OCD) and 20 healthy volunteers. The OCD group had significantly higher PsChe serum activity than in their sex- and age-matched control group. Patients' scores on the Hamilton Rating Scale for Anxiety (HRS-A) and the Beck Depression Inventory (BDI) were not correlated with their PsChe levels. The results provide additional support for the observation of higher PsChe levels among anxiety-related psychiatric conditions. However, the relationships among anxiety, depression, and PsChe appear to be complex. The nature and implications of elevated PsChe levels are still unknown.",

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N2 - Levels of pseudocholinesterase (PsChe) were measured in 20 patients with obsessive-compulsive disorder (OCD) and 20 healthy volunteers. The OCD group had significantly higher PsChe serum activity than in their sex- and age-matched control group. Patients' scores on the Hamilton Rating Scale for Anxiety (HRS-A) and the Beck Depression Inventory (BDI) were not correlated with their PsChe levels. The results provide additional support for the observation of higher PsChe levels among anxiety-related psychiatric conditions. However, the relationships among anxiety, depression, and PsChe appear to be complex. The nature and implications of elevated PsChe levels are still unknown.

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Pseudocholinesterase in obsessive-compulsive patients

Abstract

Keywords

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